The partial and integral enthalpies of mixing of liquid quaternary Ag-In-Sn-Zn alloys have been measured at 500 degrees C along seven ternary sections: In0.450Sn0.450Zn0.100, In0.375Sn0.375Zn0.250, In0.333Sn0.333Zn0.334, In0.225Sn0.550Zn0.225, In0.100Sn0.800Zn0.100, In0.550Sn0.225Zn0.225 and In0.800Sn0.100Zn0.100. The measurements were carried out using a Calvet-type microcalorimeter and drop calorimetric technique. Additionally, the enthalpies of mixing of the liquid Ag-In-Sn-Zn have been calculated using the traditional Kohler, Muggianu, Toop and Hillert geometric models and compared to the experimental one. (C) 2014 Elsevier B.V. All rights reserved.