Transparent acrylic pressure sensitive adhesives (PSAs) comprised semi-interpenetrated structured polymer networks were prepared with different co-monomer compositions. Emphasis was placed on the effect of functional groups in the co-monomer including morpholine and tetrahydrofurane moieties in the typical acrylic PSA formulation. The synthesized acrylic PSA syrups were characterized and the optical properties of the acrylic PSA film were also examined by ultraviolet-visible spectroscopy, haze meter, and prism coupler. Acrylic PSAs exhibit high transparency in the visible wavelength region. Adhesion performance was measured by the peel strength, cohesion strength, and probe tack tests. With increasing 4-acryloyl morpholine monomer concentration in the acrylic PSAs, the peel strength, cohesion strength, and probe tack increased.