화학공학소재연구정보센터
Chemistry Letters, Vol.43, No.10, 1659-1661, 2014
Symmetric Urea-catalyzed Asymmetric Michael Addition of Thiols to beta-Nitrostyrenes
Several pyrrolidine- and piperidine-based organocatalysts were evaluated for the asymmetric Michael addition of thiols to beta-nitrostyrenes. We found a structure-activity relationship between the catalyst and a higher catalytic activity for 1,3-bis [(3R,4S)-1-benzyl-4-phenylpyrrolidin-3-yl]urea.