Due to discrepancy in the standard enthalpy of formation, Delta H-f(0), of copper(II) aluminate (CuAl2O4) reported in thermodynamic databases, the calculated reaction enthalpy, Delta H-r, of CuAl2O4 with reducing gases varies considerably. In this work, the standard enthalpy of formation, Delta H-f(0), of CuAl2O4 is reassessed using the reaction enthalpy, Delta H-r, of CuAl2O4 with CO measured by differential scanning calorimetry. A value of -1824.4 +/- 4.1 kJ/mol was found for the standard enthalpy of formation, Delta H-f(0), of CuAl2O4.