The effect of yttrium and nanoclusters on the high-temperature oxidation behavior of Fe-14Cr-3W-0.4Ti nano-structured ferritic oxide dispersion-strengthened alloys was investigated. For comparison purposes, conventional stainless steels with the same chemical composition were studied as well. Long-term oxidation tests were conducted at 800 C for up to 2000 h in atmospheric air. The mass-gain versus time curves were obtained and the microstructure and chemical elements distribution in different regions of the specimens after oxidation were then analyzed by SEM/EDS and XRD. The experimental results showed that an addition of yttrium to Fe-14C-3W-0.4Ti alloy sufficiently reduced the oxidation rate. However, ODS processing to precipitate nanoclusters is a more effective means of improving high-temperature oxidation rather than a simple yttrium addition. (C) 2014 Elsevier B.V. All rights reserved.