Reactive & Functional Polymers, Vol.48, No.1-3, 119-128, 2001
Pure, homo-bifunctional poly(ethylene glycol) orthogonally protected: synthesis and characterisation
New orthogonal reversible protections have been introduced on high-molecular weight, di-hydroxy PEGs. The introduction on the reaction intermediates of a removable carboxy group allows an efficient purification from all the undesired polymeric derivatives. A final, pure high-molecular weight DMT-PEG-Fmoc has been obtained.