The discrete element method (DEM) is used for predicting the compaction behavior of two types of spray dried cemented carbide granules. The material model of the granules is determined by micromechanical experiments. First, compression tests are performed on single granules giving information of the deformation behavior at relatively small deformations. For larger deformations, nanoindentation tests are performed to give further information of the constitutive behavior indicating a strong hardening behavior at high strains. The material model is implemented in an FE model of two particles in contact and the relation between contact force and indentation depth is exported to a DEM program. The DEM program is used to simulate presently performed uniaxial die compaction experiments where the geometry of the die is taken into account. Excellent agreement is found between the experiments and the numerical predictions in the range where results from DEM simulations are valid. (C) 2013 Elsevier B.V. All rights reserved.