To control mechanical properties and to reduce planar anisotropy in Ti-Fe-O-N based high-strength titanium alloy plates, heat treatment for uni-directionally hot rolled plates and simple cross rolling process were investigated. Intense planar anisotropy in the uni-directionally rolled plates was eased by a series of heat treatment composed of solution treatment and stabilizing treatment with keeping high strength-ductility relationship. Uniform tensile properties were obtained in an annealed conditions by the simple cross rolling, in which the rolling directions were changed only once to simulate the mass-manufacturing process including slab rolling, widening and longitudinal rolling. Extremely low deformation stress of Ti-Fe-O-N alloys enables to conduct every hot rolling process in the alpha+beta temperature region even for the large sized slabs, and does contribute to the uniform mechanical properties.