The use of enzymes such as horseradish peroxidase (HRP) for degrading or removing toxic organics from synthetic wastewater has been demonstrated previously. Potential alternatives to HRP are other peroxidases, various ligninases, haloperoxidases and laccases. Results of this study indicate that a fungal peroxidase from Coprinus macrorhizus (CMP) has the capability to catalyze the same reactions as HRP. Similarly, in batch reactors the trend and removal efficiency of aromatic compounds by CMP from synthetic wastewater depend on the nature of the compound.