Journal of Physical Chemistry B, Vol.117, No.46, 14367-14371, 2013
MRI Biosensor for Lead Detection Based on the DNAzyme-Induced Catalytic Reaction
A MRI biosensor for sensitive and specific detection of lead ions (Pb2+) was developed based on DNAzyme-induced cleavage of magnetic nanoparticles (MNPs). A low limit of detection (LOD) of 0.05 ng mL-1 was obtained. This biosensor has the potential to serve as a general platform for the detection of heavy metal ions.