Reverse osmosis (RO) process is the most popular seawater desalination technology to solve global water crisis. However, the effluent of concentrated brine from RD plant could induce severe damage to marine ecosystems, especially for closed continental areas. Electrodialysis (ED) as an excellent technology has been used to treat RD effluent. An electrodialyzer which consisted of five pieces of cation-exchange membranes (CEMs) and four pieces of anion-exchange membranes (AEMs) was used to treat concentrated brine of RD plant. The effect of operation parameters such as Correia density, operating mode, type of membranes and initial brine concentration was investigated to measure a Lab-scale device. The results indicate that water transportation phenomenon through ED process are mainly induced by electroosmotic rather than osmotic water transfer clue to concentration difference. The ED process of RD concentrated brine can produce both refresh water and highly concentrated brine (ca. 27.13% (m/v)) for producing coarse salt via further crystallization. (C) 2013 Elsevier B.V. All rights reserved.