Results of experiments on critical conditions for flame acceleration and the deflagration-to-detonation transition in tubes with transverse venting are presented. Tests were made with hydrogen mixtures in two tubes (inner diameter of 46 and 92 nim) with obstacles. Ratios of vent area to total tube area were 0.2 and 0.4. Venting was shown to influence flame acceleration significantly. The greater the vent ratio, the more reactive the mixture necessary for development of fast flames. Critical conditions for flame acceleration in tubes with venting, expressed through a critical mixture expansion ratio sigma (cr), were found to be sigma (cr)/sigma (0)similar to1+2 alpha, where sigma (0) is the critical value for a closed tube. Critical conditions for detonation onset in a vented tube were found to be very close to those in a closed tube with similar configuration of obstacles.