Mediterranean basin is considered one of the most vulnerable regions of the world to climate change and with high probability to face acute water scarcity problem in the coming years. Francoli River basin (NE Spain), located in this vulnerable region is selected as a case study to evaluate the impact of climate change on the delivery of water considering the IPCC scenarios A2 and B1 for the time spans 2011-2040, 2041-2070 and 2071-2100. InVEST model is applied in a low flow river as a new case study, which reported successful results after its model validation. The studied hydrological ecosystem services will be highly impacted by climate change at Francoli River basin. Water yield is expected to be reduced between 11.5 and 44% while total drinking water provisioning will decrease between 13 and 50% having adverse consequences on the water quality of the river. Focusing at regional scale, Prades Mountains and Brugent Tributary provide most of the provision of water and also considered highly vulnerable areas to climate change. However, the most vulnerable part is the northern area which has the lowest provision of water. Francoli River basin is likely to experience desertification at this area drying Anguera and Vallverd tributaries. (C) 2013 Elsevier B.V. All rights reserved.