This paper describes the microscopic and macroscopic breakup characteristics, as well as the velocity and size distributions, of mono-dispersed droplets in relation to the breakup regimes. For this experiment, a droplet generator equipped with a piezo stack produced mono-dispersed droplets. The droplet-breakup phenomenon due to the cross-flow was captured in microscopic and macroscopic views by using the following: a spark lamp, a Nd:YAG laser, a long distance microscope and a CCD camera as a function of the Weber number. Along with the analysis of the images, the droplet size and velocity distributions were measured in the near nozzle region by a phase Doppler particle analyzer system at bag, stretching and thinning, and catastrophic breakup regimes. The results of this study showed the size and velocity distributions of disintegrated droplets at the bag, stretching and thinning, and catastrophic breakup regimes. In the bag breakup regime, the droplets separated into small and large droplets during breakup. Alternatively, the droplets disintegrated at a shorter duration and formed a cloud, similar to a fuel spray injected through an injector, in the stretching and thinning and catastrophic breakup regimes. (c) 2006 Elsevier Ltd. All rights reserved.