A simple co-precipitation method was employed to synthesize a series of cubic zinc-blende phase of ZnxCd1-xS photocatalysts using Na2S as the S source. Structural, morphological and optical properties of the samples have been investigated by XRD, SEM, EDS, XRF, ICP, N-2 physisorption and UV-vis diffuse reflectance techniques. The ZnxCd1-xS solid solution is not a simple compound mixture of ZnS and CdS, its XRD patterns show new structural peaks instead of mixture of original peaks. The lattice parameter a measured from the XRD patterns of the ZnxCd1-xS samples exhibits a slightly nonlinear relationship with the Zn mole fraction, which is slightly inconsistent with Vegard's law, thus suggesting that a nonhomogeneous alloy structure exists in ZnxCd1-xS solid solution. The photocatalytic H-2 evolution from water splitting in the sacrificial reagents of 0.25 M Na2S/0.35 M K2SO3 under visible light at 30 degrees C and 55 degrees C were also examined in the study. It is found that ZnxCd1-xS solid solution with composition x = 0.4-0.5 shows the highest photocatalytic H-2 production performance. The studied ZnxCd1-xS exhibits at least 50 h stable photocatalytic activity under outdoor sunlight irradiation. Copyright (C) 2013, Hydrogen Energy Publications, LLC. Published by Elsevier Ltd. All rights reserved.