Hydrogen combustion has many industrial applications and development of new hydrogen burners is required to fulfil new demands. A novel configuration of hydrogen burner utilizing crossflow injection of fuel jets into swirling combustion air is characterized empirically in this work. It is intended as a first step in the development of new burner technologies having reduced emission levels and improved efficiency. Experiments were designed using the full factorial design method. Operating parameters were varied simultaneously and the NOx emissions from the flame stabilized on the burner were measured. Statistical analysis of the experimental data showed that overall equivalence ratio is the dominant factor and lower NOx emissions are observed at low equivalence ratios, irrespective of the burner power level. The analysis yielded an empirical relationship among NOx emission, overall equivalence ratio, and power level that is useful in the design activity for a future combustion system based on the proposed configuration. Copyright (C) 2013, Hydrogen Energy Publications, LLC. Published by Elsevier Ltd. All rights reserved.