Preliminary studies have shown that a controlled sound field can produce enhancement of hydrogen production in a steam-reforming process. This paper expands on preliminary investigations to explain a statistical empirical model that was developed for space velocity parameters of reactor length and flow rate as well as for acoustic sound pressure level. The effects of these parameters are shown on the output of fuel conversion within a methanol-steam reformer. The experimental setup is discussed as well as the factorial method employed. Although the results of this model are particular to the experimental setup specified, this exercise statistically proves the validity of acoustic enhancement of steam reformation. The empirical model is derived and uncertainty analysis of the model takes place. Curvature was investigated for the model and was found significant for the parameter of reactor length. Linear model relationships were found adequate for sound pressure level and flow rate within the limits investigated. Preliminary results regarding the effect of frequency on the process are also discussed. (c) 2006 International Association for Hydrogen Energy. Published by Elsevier Ltd. All rights reserved.