Azeotropic separation of ethane and CO2 using reactive absorption (RA) is studied by Hysys process software. A new configuration of a RA process is proposed using diethanolamine (DEA) to break the azeotrope. Impacts of amine flow rate, amine inlet temperature and feed-inlet location are investigated to achieve an optimum condition of the process in terms of energy demand. The simulation results show that optimum values of amine flow rate, amine temperature and feed-inlet location are 1900 mole/s, 30 degrees C and 20th stage, respectively. It is found that the process including RA leads to a significant reduction in operating costs, compared to the conventional extractive process. (C) 2013 Elsevier Ltd. All rights reserved.