Low cost apartment has recently become one of the essential state policies to deal with rapid urbanisation and population boom in Vietnam. Thermal performance of a low cost apartment in Danang was examined using building simulation approach. The simulated results created by COMFIE were first calibrated by comparing them with measured data. The statistical indicators CV(RMSE) and NMBE as well as linear regression analysis were applied to assess the calibration. The calibrated model was then used to perform whole year simulations in which various ventilation and design strategies were applied. Thermal comfort potentials of these strategies were graphically defined by Brager's adaptive comfort model from which the efficiency of each strategy was quantitatively determined. In the present paper, details of the calibration approach, assessment of simulated results and comparison of the findings were discussed. Results of these analyses revealed many notable findings which are in good agreement with those obtained from other publications. The limitation and recommendations for further study are also outlined. (C) 2011 Elsevier B.V. All rights reserved.