This article shows the impacts of the extensive use of NV (natural ventilation) in the Mexican residential sector on the Mexican energy system. By integrating a thermal-airflow simulation programme with an energy systems analysis model, the impact on the Mexican energy system of replacing air conditioning, in particular, with natural ventilation to cool residential buildings is determined. It is shown that when, as in Mexico, there is a relatively simple connection between supply and electricity demand, NV creates savings which could be used to reduce either the fossil-fuel-based generation and mitigate CO2 emissions, or the use of water reservoirs and hydro generation during a dry season. (C) 2013 Elsevier Ltd. All rights reserved.