A nonenzymatic hydrogen-peroxide (H2O2) sensor was fabricated using the graphene, carbon nanotube and MnO2 hybrid as the sensing material. The hybrid was synthesized in a one-pot reaction process by chemical method. The sensor exhibited extremely high electrocatalytic activity toward the oxidation of H2O2. Under optimum conditions, the proposed biosensor can be applied to the quantification analysis of H2O2 with a wide linear range covering 1-1030 mu M (R=0.9998) and a low detection limit of 0.1 mu M. (C) 2013 Published by Elsevier Ltd.