The effects of cyclopentyl methyl ether (CPME) addition during the aqueous xylose dehydration reaction to furfural are reported here. These investigations were conducted by using pure xylose and Cynara cardunculus (cardoon) lignocellulose as sugar source and H2SO4 as catalyst. The research was also applied to aqueous solutions containing NaCl, since it has been previously demonstrated that NaCl incorporation to these reaction mixtures remarkably increases the furfural formation rate. It has been found that CPME incorporation inhibits the formation of undesired products (resins, condensation products and humins). Thus, cardoon lignocellulosic pentoses were selectively transformed into furfural (near 100%) at the following reaction conditions: 1 wt.% H2SO4, 4 wt.% biomass referred to aqueous solution, 30 min reaction, 443 K, CPME/aqueous phase mass ratio equals to 2.33, and NaCl/aqueous solution mass ratio of 0.4. In contrast, no effect was observed for cellulosic glucose transformation into hydroxymethylfurfural and levulinic acid at identical reaction conditions. (C) 2012 Elsevier Ltd. All rights reserved.