The kinetics of ozone photocatalytic decomposition in a flow-through reactor using a thin film of TiO2 coated on a glass plate is investigated. The Langmuir-Hinshelwood kinetic model provides a good description of the ozone decomposition. The effect of light intensity on reaction rate is also studied, showing a transition in the kinetic order with respect to light intensity occurred from 0.7S to 1.0 mW.cm(-2) under the experimental conditions. Fluid dynamics and surface photocatalytic reaction modeling by the computational fluid dynamic (CFD) approach is then proposed. The parameters determined in the kinetic experiment are used to calculate the ozone concentration distribution in the flow-through reactor under a given radiation field. In terms of conversion yield, the model predictions agree closely with the experimental results within the range in which the results are examined. This study presents a simple example of the photocatalytic reaction process modeling. Knowledge of the intrinsic kinetics allows the universal application of this CFD approach to the optimization and design of photocatalytic reactors.