Laboratory wastewater has neither a regular discharge cycle nor a regular discharge quantity, and its compositions are so complex that they are rather difficult to dispose of. The purpose of this study is to set up a small laboratory wastewater treatment plant, and it mainly focuses on the treatment of organic wastewater in the laboratory via supercritical water oxidation (SCWO). The process conditions optimized experimentally were the following: 440 degrees C, 26 MPa, longer than 70 s of residence time, hydrogen peroxide as oxidant with a 2.6 times excessive rate. The reaction kinetics equation was obtained through study of the degradation reaction of laboratory wastewater in supercritical water. The wastewater treatment process was simulated with the program PRO/II, and a relatively complete design scheme of a laboratory wastewater treatment process by SCWO was proposed from such aspects as the mass balance, heat balance, and equipment calculation. At the same time, an equipment prototype was established, and thus, a small laboratory wastewater treatment plant could be set up.