On the basis of the thermogravimetric analysis and scanning electron microscopy techniques, the multi-cycle chemical loop combustion (CLC) of blending fuels of coal/straw was investigated through serious experiments with alpha-Fe2O3 as the oxygen carrier. The results show that the alpha-Fe2O3 reduction reactivity is improved by blending straw into coal for more alkaline metal ash product and less ash quantity accumulation. The blended straw improves the CLC persistence, including the conversion rates of the sample combustion reaction and oxygen carrier regeneration reaction degrees, as compared to the coal fuel. It is of great significance to improve the sustainable performance of the alpha-Fe2O3 oxygen carrier by blending straw into coal.