Positron emission tomography (PET) with [F-18]-FDG can display cancerous activity depending on glucose uptake. Consequently, different PET tracers with different metabolisms are needed for further indication. We have developed multifunctional PET agents by combining Zn-62(2+) ion with laserphyrin (R) and bisglycosylated 5,10,15,20-tetrakis (pentafluorophenyl)porphyrins (H(2)Glccis-2 and H(2)Glctrans-2), which can be easily synthesized and have a half-life of 9 h. Zn-62-Labeled chemicals were successfully detected as PET signals in vivo and showed PDT-induced cell death by photoirradiation.