A F-doped V2O5-WO3/TiO2 has been developed for low-temperature selective catalytic reduction (SCR) of NO with NH3. The aim of this novel design was to improve the activity of a catalyst with low WO3 loading. Analysis by PL spectra, XRD, XPS and EPR showed that F doping improved the interaction of WO3 with TiO2 by oxygen vacancies to facilitate the formation of W5+ that was important to improve the formation of superoxide ions. The experimental results showed that NO conversion could be improved by F doping and V1W3TiF1.35 showed the highest NO removal efficiency in SCR reaction at low temperatures. (c) 2012 Elsevier B.V. All rights reserved.