Electrochemical synthesis of a novel poly(2,5-dimethoxy aniline) nanorod for ultrasensitive glucose biosensor application

D. Ragupathy; Soo Chool Lee; Salem S. Al-Deyab; A. Rajendren

Journal of Industrial and Engineering Chemistry, Vol.20, No.3, 930-936, May, 2014

DOI10.1016/j.jiec.2013.06.025 Export Citation

Electrochemical synthesis of a novel poly(2,5-dimethoxy aniline) nanorod for ultrasensitive glucose biosensor application

D. Ragupathy^†, Soo Chool Lee¹, Salem S. Al-Deyab², and A. Rajendren³

Department of Chemistry, National Institute of Technology-Puducherry, Karaikal 609 605, India
¹Department of Chemical Engineering, Kyungpook National University, Daegu 702-701, South Korea
²Department of Chemistry, Petrochemicals Research Chair, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia
³Department of Chemistry, Sir Theagaraya College, Chennai 600021, Tamil Nadu, India

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We report for the first time a rapid electrochemical synthesis of one-dimensional poly(2,5- dimethoxyaniline) nanorods (PDMA-NR) in the presence of surfactant. FE-SEM and TEM images confirm the PDMA-NR formation and the average diameter of single rod sizes in the range of ~200-300 nm. An enzymatic glucose biosensor was fabricated through immobilizing glucose oxidase (GOx) into PDMA-NR matrix. The amperometric current response of PDMA-NR/GOx to glucose is linear in the concentration range between 1 and 10 μM with a detection limit of 0.5 μM (S/N = 3). The PDMA-NR/GOx electrode possesses high sensitivity (5.03 μA/μM), selectivity, stability, and reproducibility toward glucose.

Keywords:Nanorods;Electrochemical;Surfactant;Sensitivity;Biosensor

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[Referenced By]

[1] Baughman RH, Science, 308, 63 (2005)

[2] Aleshin AN, Adv. Mater., 18(1), 17 (2006)

[3] Li D, Huang J, Kaner RB, Accounts Chem. Res., 42, 135 (2009)

[4] Chiou NR, Epstein AJ, Adv. Insect Physiol., 17, 1697 (2005)

[5] Cho SH, White SR, Braun PV, Adv. Mater., 21, 654 (2009)

[6] Gao M, Dai L, Wallace GG, Synth. Met., 137, 1393 (2003)

[7] Miao Y, Qi M, Zhan S, He N, Wang J, Yuan C, Anal. Lett., 32, 1287 (1999)

[8] Wiziack NKL, Paterno LG, Fonseca FJ, Mattoso LHC, Sens. Actuators B-Chem., 122, 484 (2007)

[9] Bilecka I, Niederberger M, Nanoscale, 2, 1358 (2010)

[10] Luo X, Vidal GD, Killard AJ, Morrin A, Smyth MR, Electroanalysis, 19, 876 (2007)

[11] Gopalan AI, Lee KP, Ragupathy D, Biosens. Bioelectron., 24, 2211 (2009)

[12] Clark LC, Lyons C, Annals of the New York Academy of Sciences, 102, 29 (1962)

[13] Ramanathan K, Pandey SS, Kumar R, Gulati A, Surya A, Murthy N, Malhotra BD, J. Appl. Polym. Sci., 78(3), 662 (2000)

[14] Ragupathy D, Gopalan AI, Lee KP, Electrochem. Commun., 11, 397 (2009)

[15] Santhosh P, Manesh KM, Uthayakumar S, Gopalan AI, Lee KP, Biosens. Bioelectron., 24, 2008 (2009)

[16] Chen WC, Wen TC, Hu CC, Gopalan A, Electrochim. Acta, 47(8), 1305 (2002)

[17] Wen TC, Chen YH, Gopalan A, Mater. Chem. Phys., 77, 559 (2002)

[18] Xia Y, Wiesinger JM, MacDiarmid AG, Epstein AJ, Chem. Mater., 7, 443 (1995)

[19] Zhang ZM, Wei ZX, Wan MX, Macromolecules, 35(15), 5937 (2002)

[20] Kumbar SG, James R, Nukavarapu SP, Laurencin CT, Nanotechnology, 3, 034002 (2008)

[21] Qin XH, Wang SY, J. Appl. Polym. Sci., 102(2), 1285 (2006)

[22] Shan D, Wang S, He Y, Xue H, Mater. Sci. Eng. C-Biomimetic Supramol. Syst., 28, 213 (2008)

[23] Pan D, Chen J, Nie L, Tao W, Yao S, Anal. Biochem., 324, 115 (2004)

[24] Garjonyte R, Malinauskas A, Sens. Actuators B-Chem., 56, 85 (1999)

[25] Santhosh P, Manesh KM, Uthayakumar S, Komathi S, Gopalan AI, Lee KP, Biochemistry, 75, 61 (2009)

[26] Xue H, Shen Z, Li Y, Synth. Met., 124, 345 (2001)

[27] Liu J, Agarwal M, Varahramyan K, Sens. Actuators B-Chem., 135, 195 (2008)

[28] Cen L, Neoh KG, Kang ET, Biosens. Bioelectron., 18, 363 (2003)

[29] Singh S, Solanki PR, Pandey MK, Malhotra BD, Sens. Actuators B-Chem., 115, 534 (2006)

[30] Fu Y, Yuan R, Chai Y, Zhou L, Zhang Y, Anal. Lett., 39, 467 (2006)

[31] Gerard M, Chaubey A, Malhotra BD, Biosens. Bioelectron., 17, 345 (2002)

[32] Cete S, Yasar A, Arslan F, Artificial Cells, Blood Substitutes, Biotechnology, 34, 367 (2006)

[33] Arslan F, Yasar A, Kilic E, J. Electrochem. Soc., 42, 137 (2006)

[34] Fiorito PA, Brett CMA, Cordoba de Torresi SI, Talanta, 69, 403 (2006)

[35] Schuhmann W, Rev. Mol. Biotech., 82, 425 (2002)

[36] Cosnier S, Anal. Biochem., 377, 507 (2003)