A nanometer-sized organic-inorganic hybrid, similar to a raspberry, comprising a repeated sequence of a three-dimensional gold nanoparticle (AuNP)-aniline oligomer-AuNP arrangement has been prepared by a single-step procedure in an aqueous medium using aniline as a reducing and protecting agent. The nanoraspberry hybrid holds a high density of highly dispersible AuNPs with a mean particle diameter of 5.0 nm, and without any contact with each other because of the linkage formed by aniline oligomers between adjacent AuNPs. The immobilization of the hybrids on a glassy carbon electrode led to the discovery of novel characteristics of the hybrids. The hybrids showed outstanding catalytic activity for the electrochemical reduction of oxygen and oxidation of glucose. This paper examines the roles of AuNPs and aniline oligomers in the development of the electrochemical catalytic property in the raspberry-like hybrid. We found that the aniline oligomer works as a linker to anchor two AuNPs in the hybrids and the individual AuNPs without any contact with each other expresses the electrochemical catalytic activity of the hybrids. (C) 2013 The Electrochemical Society. All rights reserved.