화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.21, No.11, 1241-1246, November, 2013
DOI10.1007/s13233-013-1164-9  Export Citation
Preparation and characterization of chlorinated cross-linked chitosan/cotton knit for biomedical applications
Hye Kyoung Shin, Mira Park1, Yong Sik Chung1, Hak-Yong Kim1, †, Fan-Long Jin2, Heung-Soap Choi3, and Soo-Jin Park†
  • Department of Chemistry, Inha University, Incheon, 402-751, Korea
  • 1Department of Textile Engineering, Chonbuk National University, Jeonbuk, 561-756, Korea
  • 2Department of Polymer Materials, Jilin Institute of Chemical Technology, Jilin City, 132022, P. R. China
  • 3Departments of Mechanical and Design Engineering, Hongik University, Sejong, 339-701, Korea
E-mail:,
A new cross-linked chitosan/cotton knit was prepared by the chlorination of chitosan under acidic conditions, and its active chlorine content, mechanical and antimicrobial properties, and rechargeability were characterized. The active chlorine content of the chitosan/cotton knit increased with the concentration of chitosan or sodium hypochlorite used for the treatment and showed a slight decrease upon repeated laundering. The cross-linked chitosan/cotton knit displays lower stress and higher strain than pristine cotton knit. The chlorination of the chitosan/cotton knit resulted in powerful antimicrobial activity against both gram-negative and gram-positive bacteria. For up to 30 days of storage the knit showed excellent rechargeability, taking up chlorine to nearly initial levels. Scanning electron microscope (SEM) observations indicated that chlorination did not cause the damage to the cross-linked chitosan/cotton knit.
Keywords:chitosan;cotton knit;N-halamine;active chlorine content;antimicrobial activity
  1. Periolatto M, Ferrero F, Vineis C, Carbohydr. Polym., 88, 201 (2012)
  2. Lim SH, Hudson SM, Carbohydr. Polym., 56, 227 (2004)
  3. Mocanu G, Nichifor M, Mihai D, Oproiu LC, Mater. Sci. Eng. C-Biomimetic Supramol. Syst., 33, 72 (2013)
  4. Tavaria FK, Soares JC, Reis IL, Paulo MH, Malcata FX, Pintado ME, J. Appl. Microbiol., 112(5), 1034 (2012)
  5. Fu X, Shen Y, Jiang X, Huang D, Yan Y, Carbohydr. Polym., 85, 221 (2011)
  6. Sun YY, Sun G, J. Appl. Polym. Sci., 81(3), 617 (2001)
  7. Lee US, Kim HY, Jin FL, Park SJ, J. Ind. Eng. Chem., 18(2), 792 (2012)
  8. Chiarakorn S, Pavavongsak R, Sangwatanaroj U, J. Ind. Eng. Chem., 17(3), 560 (2011)
  9. Barnes K, Liang J, Worley SD, Lee J, Broughton RM, Huang TS, J. Appl. Polym. Sci., 105(4), 2306 (2007)
  10. Ren X, Akdag A, Kocer HB, Worley SD, Broughton RM, Huang TS, Carbohydr. Polym., 78, 220 (2009)
  11. Ahmed AESI, Hay JN, Bushell ME, Wardell JN, Cavalli G, React. Funct. Polym., 68(10), 1448 (2008)
  12. Sun X, Cao Z, Porteous N, Sun Y, Acta Biomater., 8, 1498 (2012)
  13. Dong A, Lan S, Huang JF, Wang T, Zhao TY, Wang WW, Xiao LH, Zheng X, Liu FQ, Gao G, Chen YX, J. Colloid Interface Sci., 364(2), 333 (2011)
  14. Liu S, Sun G, Ind. Eng. Chem. Res., 45(19), 6477 (2006)
  15. Ren X, Kou L, Kocer HB, Zhu C, Worley SD, Broughton RM, Huang TS, Colloids Surf. A: Physicochem. Eng. Asp., 317, 711 (2008)
  16. Li R, Hu P, Ren X, Worley SD, Huang TS, Carbohydr. Polym., 92, 534 (2013)
  17. Cao Z, Sun Y, J. Biomed. Mater. Res., 85A, 99 (2008)
  18. El-tahlawy KF, El-bendary MA, Elhendawy AG, Hudson SM, Carbohydr. Polym., 60, 421 (2005)
  19. Yen MS, Huang KS, J. Appl. Polym. Sci., 78(1), 35 (2000)
  20. Yoo YC, Kim HY, Jin FL, Park SJ, Macromol. Res., 21(6), 687 (2013)
  21. Bang HJ, Kim HY, Jin FL, Woo JW, Park SJ, Bull. Korean Chem. Soc., 32, 541 (2011)
  22. Gupta D, Haile A, Carbohydr. Polym., 69, 164 (2007)
  23. Nasr HE, Sayyah SM, Essa DM, Samaha SH, Rabie AM, Carbohydr. Polym., 76, 36 (2009)
  24. El-Shafei A, Abou-Okeil A, Carbohydr. Polym., 83, 920 (2011)