The speed of sound for the binary mixtures of trichloroethylene with branched alcohols has been determined at 303.15 K. The branched alcohols include 2-propanol, 2-methyl-1-propanol, 3-methyl-1-butanol, 2-butanol, and 2-methyl-2-propanol. Further, isentropic compressibilities (K-s) and deviation in isentropic compressibilities (Delta K-s) have been computed from the sound velocity and density data derived from excess volumes. The results show that Delta K-s values are positive over the entire range of composition for the systems trichloroethylene + 3-methyl-1-butanol, + 2-butanol, and + 2-methyl-2-propanol, and an inversion of sign from negative to positive is observed for the remaining systems trichloroethylene + 2-propanol and + 2 methyl-1-propanol.