Acrylonitrile-chlorinated polyethylene-styrene copolymer (ACS resin) was prepared by a suspension polymerization and the structure of the ACS resin was characterized by IR and SEM. The influence of the chlorinated polyethylene (CPE) content, mass ratio of monomer, reaction temperature, and time on the properties of the ACS resin was investigated. With the increase of the CPE content, the thermal stability of the ACS resin decreased, the flexural strength and modulus increased, whereas the heat distortion temperature, tensile modulus, and impact strength first enhanced, and then decreased. The increase of the mass ratio of Styrene (St) to Acrylonitrile (AN) contributed to an improvement in the elongation at break, but played a negative role in the flexural strength and modulus. Increasing the reaction time and temperature could improve the performances of the ACS resin. The morphology of the ACS resin demonstrated the transformation from a brittle fracture to ductile fracture of the ACS resin with various CPE contents and supported the results of the mechanical properties. The ACS resin with good comprehensive performances could be obtained when the content of the CPE was 30%, the mass ratio of St to AN was 2/1, and the reaction condition was 80 degrees C/3 h, 110 degrees C/3 h, and 130 degrees C/2 h. (c) 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 130: 2136-2142, 2013