Numerical simulations of soot formation of n-heptane autoigniting spray in a constant-volume vessel under diesel engine conditions with different ambient densities (14.8 and 30kg/m(3)) and ambient oxygen concentrations (821% O-2 mol fraction) were performed using two-dimensional, first-order conditional moment closure (CMC). Soot formation was modeled with a semiempirical two-equation model that considers simultaneous soot particle inception, surface growth, coagulation, and oxidation by O-2 and OH. Soot radiation was accounted for with an optical-thin formulation. Results are compared to experimental data by means of ignition delay time, lift-off length, and soot volume fraction distribution. Good predictions of ignition delay and lift-off for all nine cases are achieved. High volume fraction soot location and semi-quantitative distribution have been well described even with this comparatively simple soot model. The findings suggest that the conditional moment closure approach is a promising framework for soot modeling under diesel engine conditions.