Fresh water consumption and wastewater management is a mandatory task to conserve water resources and to reduce wastewater discharge from chemical production processes. Such objectives have been addressed in many industrial sectors which consume large amounts of fresh water. Possibilities for reducing wastewater volumes by regeneration and recycling routes in the pulp and paper industry are analyzed. During pulp preparation and paper making processes by the Kraft pulping method a large amount of water is required to deliver the finished paper product. Reverse osmosis (RO) is applied for the analyses as an interception separation technology to reduce salt concentrations in wastewater streams for recycling purposes. The RO network synthesis problem is formulated as mixed integer nonlinear programming model which is solved using the general algebraic modeling system. A preliminary cost estimate indicates economic incentives by installation of RO units to avoid wastewater discharge and generate relatively clean water streams for inter-plant usage.