A series of short and steep unidirectionally migrating deep-water channels, which are typically without levees and migrate progressively northeastward, are identified in the Baiyun depression, Pearl River Mouth Basin. Using three-dimensional seismic and well data, the current study documents their morphology, internal architecture, and depositional history, and discusses the distribution and depositional controls on the bottom current reworked sands within these channels. Unidirectionally migrating deep-water channels consist of different channel-complex sets (CCSs) that are, overall, short and steep, and their northeastern walls are, overall, steeper than their southwestern counterparts. Within each CCS, bottom current reworked sands in the lower part grade upward into muddy slumps and debris-flow deposits and, finally, into shale drapes. Three stages of CCSs development are recognized: (1) the early lowstand incision stage, during which intense gravity and/or turbidity flows versus relatively weak along-slope bottom currents of the North Pacific intermediate water (NPIW-BCs) resulted in basal erosional bounding surfaces and limited bottom current reworked sands; (2) the late lowstand lateral-migration and active-fill stage, with gradual CCS widening and progressively northeastward migration, characterized by reworking of gravity- and/or turbidity-flow deposits by vigorous NPIW-BCs and the CCSs being mainly filled by bottom current reworked sands and limited slumps and debris-flow deposits; and (3) the transgression abandonment stage, characterized by the termination of the gravity and/or turbidity flows and the CCSs being widely draped by marine shales. These three stages repeated through time, leading to the generation of unidirectionally migrating deep-water channels. The distribution of the bottom current reworked sands varies both spatially and temporally. Spatially, these sands mainly accumulate along the axis of the unidirectionally migrating deep-water channels and are preferentially deposited to the side toward which the channels migrated. Temporally, these sands mainly accumulated during the late lowstand lateral-migration and active-fill stage. The bottom current reworked sands developed under the combined action of gravity and/or turbidity flows and along-slope bottom currents of NPIW-BCs. Other factors, including relative sea level fluctuations, sediment supply, and slope configurations, also affected the formation and distribution of these sands. The proposed distribution pattern of the bottom current reworked sands has practical implications for predicting reservoir occurrence and distribution in bottom current related channels.