The feasibility of performing the SO2/NOx adsorption process in a gas-solid vortex reactor (GSVR) is examined and compared with the more traditional riser technology. The multiphase reacting flow is modeled using the Eulerian-Eulerian two-fluid model. Models of nonreacting flows were validated using data from a bench-scale experimental setup. The GSVR has the potential to significantly improved heat/mass transfer between phases, as compared to more conventional fluidization technologies. Process intensification opportunities are investigated. The model predicts continuous removal efficiencies greater than 99% for SO2 and approximately 80% for NOx. The gas-solid slip velocity and convective mass transfer coefficient for the riser were 0.2-0.5 and 0.06-0.12 m/s, respectively, whereas the values for the GSVR were 6-7 and 1.0-1.1 m/s, respectively. This order of magnitude increase in the external mass transfer coefficient highlights the potential intensification opportunities provided by the GSVR.