This paper describes the combined use of carbon nanotubes and an ionic liquid directly coupled in-line to commercial CE equipment for sample treatment. The extraction unit operates as a spin column to preconcentrate the analytes. The extraction unit is inserted into the sample vial. The elution is performed in-line, placing the vial on the carrousel of the CE equipment. The joint use of carbon nanotubes and ionic liquids as sorbent is based on the high adsorption capacity of these materials, which makes them highly suitable for microextraction purposes. The LOQ of analytes were within the range of 0.650.83 mu g/L with a RSD of less than 7%. The values of recovery range between 90 and 112%. The absolute recovery obtained from samples containing 1 mu g/L of analytes was 38%.