Turkish Journal of Chemistry, Vol.25, No.3, 365-371, 2001
Lewis acid catalyzed 1,3-dipolar cycloadditon reactions of stabilized azomethine ylides
Diethylzinc was tested for the first time as the Lewis acid in 1,3-dipolar cycloaddition reactions of azomethine ylides to synthesize pyrrolidine derivatives. A new, easily applicable and highly selective method was developed for the synthesis of highly substituted pyrrolidines. By the application of this method, the synthesis of three new pyrrolidine derivatives was achieved.