The purpose of this study is to develop electrodes for electrical stimulation of the nervous system using conductive polymers, polypyrrole (PPy) and/or poly(3,4-ethylenedioxythiophene), PEDOT. We evaluated biocompatibility in fibroblast and/or myoblast of mouse. Cultured cells on PPy and/or PEDOT extended their neuritis and survived over a week. These experiments have demonstrated that conductive polymers such as PPy, PEDOT, etc. have high biocompatibility, and PPy and/or PEDOT are applicable to nerve stimulation electrodes. (C) 2010 Elsevier B.V. All rights reserved.