OSHA has recently emphasized an added commitment to do more Refinery and Chemical National Emphasis Program inspections. This article outlines company methods to (a) limit exposure and expense by supplying the agency with requested information, (b) minimize site disruptions, and (c) make compliance improvements efficiently. A successful inspection requires the development of a strategy, tactics, teams, procedures, interview process, and general management of the inspection process. (C) 2010 American Institute of Chemical Engineers Process Saf Prog 29: 393-395, 2010