Runaway reactions continue to be a problem in the chemical industry. A recent study showed that 26.5% of our major chemical plant accidents are due to runaways. This article reviews the a) historical perspective of runaways, b) state of our knowledge of bow to detect potential runaways, since detection is a key element of a successful inhibition process, and c) state of our knowledge on bow to shortstop, or inhibit, reaction. The objective of the research is to improve our plants safety performance in a) identifying methods for successfully inhibiting runaway reactions under adverse conditions, and b) highlighting future problems and limitations, as reactions are faster and reactors more complex. Computational Fluid Dynamics (Fluent) is the tool used in this study.