The chemical process industries (CPI) handling hazardous chemicals can be rather attractive targets for deliberate adversarial actions by terrorists, criminals and disgruntled employees. The damage inflicted may include casualties, economic loss and political fallout. There is an urgent need for each facility to have a security management programme. Its essential components are security risk assessment, security countermeasures and emergency response. Security risk assessment can be carried out qualitatively by threat analysis, vulnerability analysis and developing a Security Risk Factor Table (SRFT). All these are discussed at length. Security countermeasures are the steps taken to strengthen the weak points in a system, either by lessening vulnerabilities or by hardening the facilities. Various security countermeasures are suggested for improving security of CPI. Appropriate emergency response measures that could mitigate the consequences of a successful attack are also discussed in the paper. It is recommended that many of the conventional safety and security measures adopted thus far may have to be modified in light of the enhanced and complex nature of the present security threats.