Flash point is a primary property used to determine the fire and explosion hazards of a liquid. Minimum flash point behaviour (MFPB) is exhibited when the flash point of a mixture is below the flash points of the individual components. The identification of this behaviour is critical, because a hazardous situation results from taking the lowest component flash point value as the mixture flash point. Even for experimental measurements, ail estimate of the Mixture flash point is needed. A procedure to estimate the flash point of binary mixtures is discussed. Predictions for the aqueous mixtures methanol-water and ethanol-water are presented and compared with experimental values as well as for the flammable mixtures octane-ethanol and octane-l-butanol, which exhibit MFPB. Quantum chemical calculation methods such as COSMO-RS and theoretical methods such as UNIFAC were evaluated for the prediction of MFPB mixtures.