Cotton fabrics were pregrafted with mixed monomer of methacrylic acid (MAA) and N-methylolacrylamide (MAM) before undergoing finishing with 1,3-dimethylolethylene urea. Experiments show that when the molar ratio of MAA and MAM is 4 : 6 the finished fabric has the maximum nitrogen content (N%) and crosslinking density. The pregrafting can improve the wet crease recovery angle and the moisture regain, can reduce the tensile strength retention, and has little effect on the dry crease recovery angle. In addition, at a pregrafting ratio of 4 : 6, the finished fabric has the highest crease recovery angle and moisture regain.