The hydrolysis of dichlorodifluoromethane (CFC-12) was investigated using alumina-zirconia catalysts, which exhibited high performance during the oxidative decomposition of chloropentafluoroethane (CFC-115) in the presence of butane. The CFC-12 conversion increased during the hydrolysis of CFC-12 over alumina-zirconia catalysts. X-ray diffraction patterns and temperature-programmed desorption profiles of ammonia revealed the formation of a new acid site induced by the halogen atoms and water vapor formed during hydrolysis.