A hybrid mathematic model for pervaporation is proposed which incorporates the concepts of solution-diffusion model and pore model. The model allows performance prediction as well as the establishment of the internal concentration and pressure profiles within the membrane. The model parameters specific to the particular membrane and mixture system are determined using liquid sorption and pervaporation experimental data. The model is experimentally examined using ethanol-water mixtures and poly(dimethyl siloxane)-poly(vinyldiene fluoride) (PDMS-PVDF) composite membranes. The characteristics of flux and separation factor predicted using the model are in fair agreement with the experimental data under various feed concentrations and downstream pressures for different membrane arrangements, including single-layer, reverse single-layer and double-layer PDMS-PVDF composite membranes. Internal profiles of pressure, concentration and component mole fraction can be established using the model. Concentration polarization phenomena for ethanol and water are located at membrane interfaces and vapor-liquid interfaces, respectively. Performances of several different membrane designs are compared using the model. (c) 2007 Taiwan Institute of Chemical Engineers. Published by Elsevier B.V. All rights reserved.