Saturated vapor pressure of 2-chloromethylbenzoxazole was measured at temperatures from 347.65 K to 424.55 K and correlated with the Antoine equation. The isobaric VLE equilibrium data of the binary system 2-chloromethylbenzoxazole and chlorobenzene were determined at 7.92 kPa and 10.59 kPa and examined with the Herington thermodynamic consistency test and the chi(2) test. The experimental data were correlated with the UNIQUAC model. The optimum parameters of the UNIQUAC model were determined by the least-squares regression method. Deviations between experimental and calculated data were 0.00983 at 7.92 kPa and 0.01317 at 10.59 kPa.