Biotechnology Progress

Biotechnology Progress, Vol.34, No.3 Entire volume, number list

ISSN: 8756-7938 (Print)

In this Issue (26 articles)

557 - 557	Finding the proverbial needle in the haystack...& then what? Clonally-Derived cell lines Domach M
558 - 558	Response to "Statistical analysis of data from limiting dilution cloning to assess monoclonality in generating manufacturing cell lines" Savery J, Evans K
559 - 569	Beating the odds: The poisson distribution of all input cells during limiting dilution grossly underestimates whether a cell line is clonally-derived or not Zhou YZ, Shaw D, Lam C, Tsukuda J, Yim M, Tang DM, Louie S, Laird MW, Snedecor B, Misaghi S
570 - 583	Effective and efficient characterization of Chinese hamster ovary production cell lines using automated intracellular staining and statistical modeling Krebs LE, Bowden DM, Bray CM, Shaw MM, Frye CC
584 - 592	Development and characterization of an automated imaging workflow to generate clonally-derived cell lines for therapeutic proteins Shaw D, Yim M, Tsukuda J, Joly JC, Lin A, Snedecor B, Laird MW, Lang SE
593 - 601	Measuring the aggregation of CHO cells prior to single cell cloning allows a more accurate determination of the probability of clonality Klottrup KJ, Miro-Quesada G, Flack L, Pereda I, Hawley-Nelson P
602 - 612	Analytical subcloning of a clonal cell line demonstrates cellular heterogeneity that does not impact process consistency or robustness Scarcelli JJ, Hone M, Beal K, Ortega A, Figueroa B, Starkey JA, Anderson K
613 - 623	Characterization of phenotypic and genotypic diversity in subclones derived from a clonal cell line Tharmalingam T, Barkhordarian H, Tejeda N, Daris K, Yaghmour S, Yam P, Lu F, Goudar C, Munro T, Stevens J
624 - 634	Probing the importance of clonality: Single cell subcloning of clonally derived CHO cell lines yields widely diverse clones differing in growth, productivity, and product quality Ko P, Misaghi S, Hu ZL, Zhan DJ, Tsukuda J, Yim M, Sanford M, Shaw D, Shiratori M, Snedecor B, Laird M, Shen A
635 - 649	Antibody expression stability in CHO clonally derived cell lines and their subclones: Role of methylation in phenotypic and epigenetic heterogeneity Patel NA, Anderson CR, Terkildsen SE, Davis RC, Pack LD, Bhargava S, Clarke HRG
650 - 658	Development of a novel affinity chromatography resin for platform purification of bispecific antibodies with modified protein a binding avidity Tustian AD, Laurin L, Ihre H, Tran T, Stairs R, Bak H
659 - 670	Monitoring mAb cultivations with in-situ raman spectroscopy: The influence of spectral selectivity on calibration models and industrial use as reliable PAT tool Santos RM, Kessler JM, Salou P, Menezes JC, Peinado A
671 - 680	One-pot strategy for on-site enzyme production, biomass hydrolysis, and ethanol production using the whole solid-state fermentation medium of mixed filamentous fungi Maehara L, Pereira SC, Silva AJ, Farinas CS
681 - 691	Analysis of Recombinant Human Serum Albumin Extraction and Degradation in Transgenic Rice Extracts Sheshukova KA, Wilken LR
692 - 701	Rapid fabrication of detachable three-dimensional tissues by layering of cell sheets with heating centrifuge Haraguchi Y, Kagawa Y, Hasegawa A, Kubo H, Shimizu T
702 - 710	Effects of ultrasonication variables on the activity and properties of alpha amylase preparation Tran TTT, Nguyen KT, Le VVM
711 - 720	Surfactant selection for a liquid foam-bed photobioreactor Janoska A, Vazquez M, Janssen M, Wijffels RH, Cuaresma M, Vilchez C
721 - 729	Selective extraction of lipase and amylase from enzyme mixture by employing liquid emulsion membrane Priyanka BS, Rastogi NK
730 - 737	Development of generic raman models for a GS-KOTM CHO platform process Webster TA, Hadley BC, Hilliard W, Jaques C, Mason C
738 - 745	Investigation of the free heavy chain homodimers of a monoclonal antibody Chung H, Buck L, Daris K, Welborn B, Luo QZ, Wypych J
746 - 755	Extraction of bioactive compounds against cardiovascular diseases from Lentinula edodes using a sequential extraction method Morales D, Piris AJ, Ruiz-Rodriguez A, Prodanov M, Soler-Rivas C
756 - 766	Probing lactate metabolism variations in large-scale bioreactors Xu S, Jiang RB, Mueller R, Hoesli N, Kretz T, Bowers J, Chen H
767 - 777	Physicochemical and catalytic properties of acylase I from aspergillus melleus immobilized on amino- and carbonyl-grafted stober silica Kolodziejczak-Radzimska A, Zdarta J, Jesionowski T
778 - 783	Cryopreservation of chicken blastodermal cells and their quality assessment by flow cytometry and transmission electron microscopy Svoradova A, Kuzelova L, Vasicek J, Olexikova L, Chrenek P
784 - 792	Covalent immobilization of halohydrin dehalogenase for efficient synthesis of epichlorohydrin in an integrated bioreactor Zou SP, Gu K, Zheng YG
793 - 805	Metabolic responses and pathway changes of mammalian cells under different culture conditions with media supplementations Park SY, Reimonn TM, Agarabi CD, Brorson KA, Yoon S