International Journal of Molecular Sciences

International Journal of Molecular Sciences, Vol.15, No.3 Entire volume, number list

ISSN: 1422-0067 (Print)

In this Issue (105 articles)

3356 - 3372	Galectin-9 Induced Myeloid Suppressor Cells Expand Regulatory T Cells in an IL-10-Dependent Manner in CVB3-Induced Acute Myocarditis Zhang YY, Jiang L, Zhang MY, Lv K
3373 - 3388	Development of Lipid-Shell and Polymer Core Nanoparticles with Water-Soluble Salidroside for Anti-Cancer Therapy Fang DL, Chen Y, Xu B, Ren K, He ZY, He LL, Lei Y, Fan CM, Song XR
3389 - 3402	Improved Establishment of Embryonic Stem (ES) Cell Lines from the Chinese Kunming Mice by Hybridization with 129 Mice Yu SM, Yan XR, Liu HH, Cai X, Cao SZ, Shen LH, Zuo ZC, Deng JL, Ma XP, Wang Y, Ren Z
3403 - 3431	Genotoxic Anti-Cancer Agents and Their Relationship to DNA Damage, Mitosis, and Checkpoint Adaptation in Proliferating Cancer Cells Swift LH, Golsteyn RM
3432 - 3443	Genistein-Inhibited Cancer Stem Cell-Like Properties and Reduced Chemoresistance of Gastric Cancer Huang WF, Wan CP, Luo QC, Huang ZJ, Luo Q
3481 - 3494	Purification and Characterization of Aporphine Alkaloids from Leaves of Nelumbo nucifera Gaertn and Their Effects on Glucose Consumption in 3T3-L1 Adipocytes Ma CJ, Wang JJ, Chu HM, Zhang XX, Wang ZH, Wang HL, Li G
3495 - 3506	PseAAC-General: Fast Building Various Modes of General Form of Chou's Pseudo-Amino Acid Composition for Large-Scale Protein Datasets Du PF, Gu SW, Jiao YS
3507 - 3518	HBx Protein Promotes Oval Cell Proliferation by Up-Regulation of Cyclin D1 via Activation of the MEK/ERK and PI3K/Akt Pathways Wang HY, Yang SL, Liang HF, Li CH
3519 - 3532	Docetaxel-Loaded Chitosan Microspheres as a Lung Targeted Drug Delivery System: In Vitro and in Vivo Evaluation Wang H, Xu YD, Zhou X
3533 - 3545	Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits Lauer K
3546 - 3559	Association between Single Nucleotide Polymorphism rs1044925 and the Risk of Coronary Artery Disease and Ischemic Stroke Wu DF, Yin RX, Cao XL, Chen WX
3560 - 3579	Activation of VCAM-1 and Its Associated Molecule CD44 Leads to Increased Malignant Potential of Breast Cancer Cells Wang PC, Weng CC, Hou YS, Jian SF, Fang KT, Hou MF, Cheng KH
3580 - 3595	Interactive Association of Drugs Binding to Human Serum Albumin Yang F, Zhang Y, Liang H
3596 - 3611	Non-Specific Inhibition of Ischemia- and Acidosis-Induced Intracellular Calcium Elevations and Membrane Currents by alpha-Phenyl-N-tert-butylnitrone, Butylated Hydroxytoluene and Trolox Katnik C, Cuevas J
3612 - 3623	Transport of Glial Cell Line-Derived Neurotrophic Factor into Liposomes across the Blood-Brain Barrier: In Vitro and in Vivo Studies Wu SL, Li GQ, Li X, Lin CN, Yu D, Luan S, Ma C
3624 - 3639	Anthelmintic Activities of Aporphine from Nelumbo nucifera Gaertn. cv. Rosa-plena against Hymenolepis nana Lin RJ, Wu MH, Ma YH, Chung LY, Chen CY, Yen CM
3640 - 3659	An Overview of Poly(lactic-co-glycolic) Acid (PLGA)-Based Biomaterials for Bone Tissue Engineering Gentile P, Chiono V, Carmagnola I, Hatton PV
3660 - 3670	A Proteomic Approach of Bradyrhizobium/Aeschynomene Root and Stem Symbioses Reveals the Importance of the fixA Locus for Symbiosis Delmotte N, Mondy S, Alunni B, Fardoux J, Chaintreuil C, Vorholt JA, Giraud E, Gourion B
3671 - 3697	Nanotoxicity Overview: Nano-Threat to Susceptible Populations Li Y, Zhang Y, Yan B
3698 - 3710	Multilineage Potential Research of Bovine Amniotic Fluid Mesenchymal Stem Cells Gao YH, Zhu ZQ, Zhao YH, Hua JL, Ma YH, Guan WJ
3711 - 3728	Exposure to Diflubenzuron Results in an Up-Regulation of a Chitin Synthase 1 Gene in Citrus Red Mite, Panonychus citri (Acari: Tetranychidae) Xia WK, Ding TB, Niu JZ, Liao CY, Zhong R, Yang WJ, Liu B, Dou W, Wang JJ
3729 - 3745	Effect of NK4 Transduction in Bone Marrow-Derived Mesenchymal Stem Cells on Biological Characteristics of Pancreatic Cancer Cells Sun YP, Zhang BL, Duan JW, Wu HH, Wang BQ, Yu ZP, Yang WJ, Shan YF, Zhou MT, Zhang QY
3746 - 3767	Killing Me Softly-Future Challenges in Apoptosis Research Westhoff MA, Bruhl O, Nonnenmacher L, Karpel-Massler G, Debatin KM
3768 - 3783	Three-Dimensional Structural Aspects of Protein-Polysaccharide Interactions Nagae M, Yamaguchi Y
3784 - 3798	Inhibition of Acetylcholinesterase Modulates NMDA Receptor Antagonist Mediated Alterations in the Developing Brain Bendix I, Serdar M, Herz J, von Haefen C, Nasser F, Rohrer B, Endesfelder S, Felderhoff-Mueser U, Spies CD, Sifringer M
3799 - 3815	Comparative Transcriptional Profiling of Three Super-Hybrid Rice Combinations Peng YG, Wei G, Zhang L, Liu GZ, Wei XL, Zhu Z
3816 - 3833	Role of A20 in cIAP-2 Protection against Tumor Necrosis Factor alpha (TNF-alpha)-Mediated Apoptosis in Endothelial Cells Guo SZ, Messmer-Blust AF, Wu JP, Song XX, Philbrick MJ, Shie JL, Rana JS, Li J
3834 - 3841	Novel Missense Mutation in the NOD2 Gene in a Patient with Early Onset Ulcerative Colitis: Causal or Chance Association? Girardelli M, Vuch J, Tommasini A, Crovella S, Bianco AM
3842 - 3859	Calcium Imaging Perspectives in Plants Kanchiswamy CN, Malnoy M, Occhipinti A, Maffei ME
3860 - 3870	Inhibition of Aflatoxin Synthesis in Aspergillus flavus by Three Structurally Modified Lentinans Ma JY, Mo HZ, Chen Y, Ding D, Hu LB
3871 - 3888	Isolation and Characterization of the Brassinosteroid Receptor Gene (GmBRI1) from Glycine max Wang M, Sun S, Wu CX, Han TF, Wang QY
3889 - 3903	Osthole Suppresses the Migratory Ability of Human Glioblastoma Multiforme Cells via Inhibition of Focal Adhesion Kinase-Mediated Matrix Metalloproteinase-13 Expression Tsai CF, Yeh WL, Chen JH, Lin CJ, Huang SS, Lu DY
3904 - 3925	Nanomedicine-Based Neuroprotective Strategies in Patient Specific-iPSC and Personalized Medicine Jang SF, Liu WH, Song WS, Chiang KL, Ma HI, Kao CL, Chen MT
3926 - 3951	Synthesis of Analogues of Gingerol and Shogaol, the Active Pungent Principles from the Rhizomes of Zingiber officinale and Evaluation of Their Anti-Platelet Aggregation Effects Shih HC, Chern CY, Kuo PC, Wu YC, Chan YY, Liao YR, Teng CM, Wu TS
3952 - 3969	Mitochondria in the Center of Human Eosinophil Apoptosis and Survival Ilmarinen P, Moilanen E, Kankaanranta H
3970 - 3988	Antioxidant Properties and PC12 Cell Protective Effects of a Novel Curcumin Analogue (2E,6E)-2,6-Bis(3,5-dimethoxybenzylidene)cyclohexanone (MCH) Ao GZ, Chu XJ, Ji YY, Wang JW
3989 - 4006	Increased Circulatory Asymmetric Dimethylarginine and Multiple Organ Failure: Bile Duct Ligation in Rat as a Model Sheen JM, Chen YC, Tain YL, Huang LT
4007 - 4018	miR-21 Promotes Human Nucleus Pulposus Cell Proliferation through PTEN/AKT Signaling Liu HZ, Huang XW, Liu XY, Xiao S, Zhang Y, Xiang TC, Shen XJ, Wang GP, Sheng B
4019 - 4030	The Effect and Mechanism of Tamoxifen-Induced Hepatocyte Steatosis in Vitro Zhao F, Xie P, Jiang JL, Zhang LQ, An W, Zhan YT
4031 - 4048	Role of miR-191/425 Cluster in Tumorigenesis and Diagnosis of Gastric Cancer Peng WZ, Ma R, Wang F, Yu J, Liu ZB
4049 - 4059	Perineural Dexmedetomidine Attenuates Inflammation in Rat Sciatic Nerve via the NF-kappa B Pathway Huang Y, Lu Y, Zhang L, Yan J, Jiang J, Jiang H
4060 - 4076	Long Non-Coding RNA HOTAIR Promotes Cell Migration and Invasion via Down-Regulation of RNA Binding Motif Protein 38 in Hepatocellular Carcinoma Cells Ding CF, Cheng SB, Yang Z, Lv Z, Xiao H, Du CL, Peng CH, Xie HY, Zhou L, Wu J, Zheng SS
4077 - 4087	Influence of Diet, Menstruation and Genetic Factors on Iron Status: A Cross-Sectional Study in Spanish Women of Childbearing Age Blanco-Rojo R, Toxqui L, Lopez-Parra AM, Baeza-Richer C, Perez-Granados AM, Arroyo-Pardo E, Vaquero MP
4088 - 4103	Endogenous Nitric-Oxide Synthase Inhibitor ADMA after Acute Brain Injury Jung CS, Wispel C, Zweckberger K, Beynon C, Hertle D, Sakowitz OW, Unterberg AW
4104 - 4125	Influence of Interferon-Alpha Combined with Chemo (Radio) Therapy on Immunological Parameters in Pancreatic Adenocarcinoma Karakhanova S, Mosl B, Harig S, von Ahn K, Fritz J, Schmidt J, Jager D, Werner J, Bazhin AV
4126 - 4141	Alcohol Induced Hepatic Degeneration in a Hepatitis C Virus Core Protein Transgenic Mouse Model Noh DH, Lee EJ, Kim AY, Lee EM, Min CW, Kang KK, Lee MM, Kim SH, Sung SE, Hwang M, Yu DY, Jeong KS
4142 - 4157	Exosomes Derived from Mesenchymal Stem Cells Yu B, Zhang XM, Li XR
4158 - 4188	Modulation of Gut Microbiota in the Management of Metabolic Disorders: The Prospects and Challenges Erejuwa OO, Sulaiman SA, Ab Wahab MS
4189 - 4200	Construction and Analysis of Siberian Tiger Bacterial Artificial Chromosome Library with Approximately 6.5-Fold Genome Equivalent Coverage Liu CQ, Bai CY, Guo Y, Liu D, Lu TF, Li XC, Ma JZ, Ma YH, Guan WJ
4201 - 4220	Synergistic Enhancement of Cancer Therapy Using a Combination of Ceramide and Docetaxel Feng LX, Li M, Liu YJ, Yang SM, Zhang N
4221 - 4236	Structure of N-Terminal Sequence Asp-Ala-Glu-Phe-Arg-His-Asp- Ser of A beta-Peptide with Phospholipase A(2) from Venom of Andaman Cobra Sub-Species Naja naja sagittifera at 2.0 angstrom Resolution Mirza Z, Pillai VG, Zhong WZ
4237 - 4254	The First Insight into the Metabolite Profiling of Grapes from Three Vitis vinifera L. Cultivars of Two Controlled Appellation (DOC) Regions Teixeira A, Martins V, Noronha H, Eiras-Dias J, Geros H
4255 - 4256	Synthesis and Characterization of Naphthalenediimide-Functionalized Flavin Derivatives (vol 14, pg 7468, 2013) Zainalabdeen N, Fitzpatrick B, Kareem MM, Nandwana V, Cooke G, Rotello VM
4257 - 4272	Synthesis, Antifungal Activities and Qualitative Structure Activity Relationship of Carabrone Hydrazone Derivatives as Potential Antifungal Agents Wang H, Ren SX, He ZY, Wang DL, Yan XN, Feng JT, Zhang X
4273 - 4283	Polymorphisms in DNA Repair Genes (APEX1, XPD, XRCC1 and XRCC3) and Risk of Preeclampsia in a Mexican Mestizo Population Sandoval-Carrillo A, Mendez-Hernandez EM, Vazquez-Alaniz F, Aguilar-Duran M, Tellez-Valencia A, Barraza-Salas M, Castellanos-Juarez FX, La Llave-Leon O, Salas-Pacheco JM
4284 - 4298	Detection of Borreliae in Archived Sera from Patients with Clinically Suspect Lyme Disease Lee SH, Vigliotti JS, Vigliotti VS, Jones W, Shearer DM
4299 - 4317	The Effect of Physical and Chemical Cues on Hepatocellular Function and Morphology Abdellatef SA, Ohi A, Nabatame T, Taniguchi A
4318 - 4332	The Pro-Apoptotic Role of the Regulatory Feedback Loop between miR-124 and PKM1/HNF4 alpha in Colorectal Cancer Cells Sun Y, Zhao XP, Luo M, Zhou YH, Ren WY, Wu KF, Li X, Shen JP, Hu Y
4333 - 4355	Comparative Proteomic Analysis of Differential Responses of Pinus massoniana and Taxus wallichiana var. mairei to Simulated Acid Rain Hu WJ, Chen J, Liu TW, Simon M, Wang WH, Chen J, Wu FH, Liu X, Shen ZJ, Zheng HL
4356 - 4392	Sphingolipids: Key Regulators of Apoptosis and Pivotal Players in Cancer Drug Resistance Giussani P, Tringali C, Riboni L, Viani P, Venerando B
4393 - 4414	Intratumoral Decorin Gene Delivery by AAV Vector Inhibits Brain Glioblastomas and Prolongs Survival of Animals by Inducing Cell Differentiation Ma HI, Hueng DY, Shui HA, Han JM, Wang CH, Lai YH, Cheng SY, Xiao X, Chen MT, Yang YP
4415 - 4430	Carvacrol and trans-Cinnamaldehyde Reduce Clostridium difficile Toxin Production and Cytotoxicity in Vitro Mooyottu S, Kollanoor-Johny A, Flock G, Bouillaut L, Upadhyay A, Sonenshein AL, Venkitanarayanan K
4431 - 4441	Transplanted Neural Stem Cells Modulate Regulatory T, gamma delta T Cells and Corresponding Cytokines after Intracerebral Hemorrhage in Rats Gao L, Lu Q, Huang LJ, Ruan LH, Yang JJ, Huang WL, ZhuGe WS, Zhang YL, Fu B, Jin KL, ZhuGe QC
4442 - 4452	Comparison of the Osteogenic Potential of Titanium and Modified Zirconia-Based Bioceramics Cho YD, Shin JC, Kim HL, Gerelmaa M, Yoon HI, Ryoo HM, Kim DJ, Han JS
4453 - 4463	Exercise Pretreatment Promotes Mitochondrial Dynamic Protein OPA1 Expression after Cerebral Ischemia in Rats Zhang L, He ZJ, Zhang Q, Wu Y, Yang XJ, Niu WX, Hu YS, Jia J
4464 - 4480	Effect of Nitrate on Nodule and Root Growth of Soybean (Glycine max ( L.) Merr.) Saito A, Tanabata S, Tanabata T, Tajima S, Ueno M, Ishikawa S, Ohtake N, Sueyoshi K, Ohyama T
4481 - 4491	Proteomic Analysis of the Follicular Fluid of Tianzhu White Yak during Diestrus Tao JZ, Zhao GS, Zhao XX, Li FD, Wu XH, Hu JJ, Zhang Y
4492 - 4522	Towards Controlling the Glycoform: A Model Framework Linking Extracellular Metabolites to Antibody Glycosylation Jedrzejewski PM, del Val IJ, Constantinou A, Dell A, Haslam SM, Polizzi KM, Kontoravdi C
4523 - 4530	A Preliminary X-ray Study of Murine Tnfaip8/Oxi-alpha Lee D, Kim MS, Park J, Jhon GJ, Son JH, Shin DH
4531 - 4549	Structural and Molecular Modeling Features of P2X Receptors Alves LA, da Silva JHM, Ferreira DNM, Fidalgo-Neto AA, Teixeira PCN, de Souza CAM, Caffarena ER, de Freitas MS
4550 - 4564	New Unsymmetrically Benzene-Fused Bis (Tetrathiafulvalene): Synthesis, Characterization, Electrochemical Properties and Electrical Conductivity of Their Materials Abbaz T, Bendjeddou A, Gouasmia A, Villemin D, Shirahata T
4565 - 4582	New Insights on Plant Cell Elongation: A Role for Acetylcholine Di Sansebastiano GP, Fornaciari S, Barozzi F, Piro G, Arru L
4583 - 4607	Transcriptome Expression Profiling in Response to Drought Stress in Paulownia australis Dong YP, Fan GQ, Zhao ZL, Deng MJ
4608 - 4618	8-Alkylcoumarins from the Fruits of Cnidium monnieri Protect against Hydrogen Peroxide Induced Oxidative Stress Damage Chang CI, Hu WC, Shen CP, Hsu BD, Lin WY, Sung PJ, Wang WH, Wu JB, Kuo YH
4619 - 4634	Testosterone Reduces Knee Passive Range of Motion and Expression of Relaxin Receptor Isoforms via 5 alpha-Dihydrotestosterone and Androgen Receptor Binding Dehghan F, Muniandy S, Yusof A, Salleh N
4635 - 4656	Genome-Wide Analysis of the RNA Helicase Gene Family in Gossypium raimondii Chen J, Zhang YJ, Liu JB, Xia MX, Wang W, Shen FF
4657 - 4670	Influence of Green, Red and Blue Light Emitting Diodes on Multiprotein Complex Proteins and Photosynthetic Activity under Different Light Intensities in Lettuce Leaves (Lactuca sativa L.) Muneer S, Kim EJ, Park JS, Lee JH
4671 - 4713	Tau Protein Modifications and Interactions: Their Role in Function and Dysfunction Mietelska-Porowska A, Wasik U, Goras M, Filipek A, Niewiadomska G
4714 - 4732	Current Progress in Bioactive Ceramic Scaffolds for Bone Repair and Regeneration Gao CD, Deng YW, Feng P, Mao ZZ, Li PJ, Yang B, Deng JJ, Cao YY, Shuai CJ, Peng SP
4733 - 4746	Nitric Oxide Functions as a Signal in Ultraviolet-B-Induced Baicalin Accumulation in Scutellaria baicalensis Suspension Cultures Zhang JJ, Li XQ, Sun JW, Jin SH
4747 - 4779	The Role of Chemokines in Hepatitis C Virus-Mediated Liver Disease Brass A, Brenndorfer ED
4780 - 4794	Over-Expression of Platelet-Derived Growth Factor-D Promotes Tumor Growth and Invasion in Endometrial Cancer Wang Y, Qiu HF, Hu WX, Li SR, Yu JJ
4795 - 4822	Toxicological Assessment of Inhaled Nanoparticles: Role of in Vivo, ex Vivo, in Vitro, and in Silico Studies Frohlich E, Salar-Behzadi S
4823 - 4836	Identification of the Novel Interacting Partners of the Mammalian Target of Rapamycin Complex 1 in Human CCRF-CEM and HEK293 Cells Rahman H, Qasim M, Oellerich M, Asif AR
4837 - 4855	The Growth Hormone Secretagogue Receptor: Its Intracellular Signaling and Regulation Yin Y, Li Y, Zhang WZ
4856 - 4877	Dimers of G-Protein Coupled Receptors as Versatile Storage and Response Units Parker MS, Sah R, Balasubramaniam A, Park EA, Sallee FR, Parker SL
4878 - 4902	Comparative Molecular Dynamics Simulations of Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 Lindin I, Wuxiuer Y, Ravna AW, Moens U, Sylte I
4903 - 4914	Phosphosite Mapping of HIP-55 Protein in Mammalian Cells Liu N, Sun NN, Gao X, Li ZJ
4915 - 4937	iNR-Drug: Predicting the Interaction of Drugs with Nuclear Receptors in Cellular Networking Fan YN, Xiao X, Min JL, Chou KC
4938 - 4945	Calcium and Vitamin D in the Regulation of Energy Balance: Where Do We Stand? Soares MJ, Pathak K, Calton EK
4946 - 4964	Exogenous Asymmetric Dimethylarginine (ADMA) in Pathogenesis of Ischemia-Reperfusion-Induced Gastric Lesions: Interaction with Protective Nitric Oxide (NO) and Calcitonin Gene-Related Peptide (CGRP) Magierowski M, Jasnos K, Sliwowski Z, Surmiak M, Krzysiek-Maczka G, Ptak-Belowska A, Kwiecien S, Brzozowski T
4965 - 4976	P-Glycoprotein and Drug Resistance in Systemic Autoimmune Diseases Picchianti-Diamanti A, Rosado MM, Scarsella M, Lagana B, D'Amelio R
4977 - 4993	The Multiple Mechanisms of Cell Death Triggered by Resveratrol in Lymphoma and Leukemia Frazzi R, Tigano M
4994 - 5010	Investigation into Variation of Endogenous Metabolites in Bone Marrow Cells and Plasma in C3H/He Mice Exposed to Benzene Sun RL, Zhang J, Yin LH, Pu YP
5011 - 5031	Bovine Induced Pluripotent Stem Cells Are More Resistant to Apoptosis than Testicular Cells in Response to Mono-(2-ethylhexyl) Phthalate Lin YC, Kuo KK, Wuputra K, Lin SH, Ku CC, Yang YH, Wang SW, Wang SW, Wu DC, Wu CC, Chai CY, Lin CL, Lin CS, Kajitani M, Miyoshi H, Nakamura Y, Hashimoto S, Matsushima K, Jin C, Huang SK, Saito S, Yokoyama KK
5032 - 5044	Atmospheric Oxidation Mechanism and Kinetic Studies for OH and NO3 Radical-Initiated Reaction of Methyl Methacrylate Gao R, Zhu LD, Zhang QZ, Wang WX
5045 - 5062	A Caspase-Dependent Pathway Is Involved in Wnt/beta-Catenin Signaling Promoted Apoptosis in Bacillus Calmette-Guerin Infected RAW264.7 Macrophages Wu XL, Deng GC, Hao XJ, Li Y, Zeng J, Ma CY, He YL, Liu XM, Wang YJ
5063 - 5078	A Chrysanthemum Heat Shock Protein Confers Tolerance to Abiotic Stress Song AP, Zhu XR, Chen FD, Gao HS, Jiang JF, Chen SM
5079 - 5093	Differential Transcriptome Analysis between Paulownia fortunei and Its Synthesized Autopolyploid Zhang XS, Deng MJ, Fan GQ
5094 - 5114	No Stress! Relax! Mechanisms Governing Growth and Shape in Plant Cells Guerriero G, Hausman JF, Cai G
5115 - 5127	Synthesis and Biological Evaluation of 2-Aminobenzamide Derivatives as Antimicrobial Agents: Opening/Closing Pharmacophore Site Mabkhot YN, Al-Majid AM, Barakat A, Al-Showiman SS, Al-Har MS, Radi S, Naseer MM, Hadda TB
5128 - 5139	Application of Computational Methods for the Design of BACE-1 Inhibitors: Validation of in Silico Modelling Bajda M, Jonczyk J, Malawska B, Filipek S
5140 - 5162	Structure and Antitumor and Immunomodulatory Activities of a Water-Soluble Polysaccharide from Dimocarpus longan Pulp Meng FY, Ning YL, Qi J, He Z, Jie J, Lin JJ, Huang YJ, Li FS, Li XH
5163 - 5174	Albumin Suppresses Human Hepatocellular Carcinoma Proliferation and the Cell Cycle Nojiri S, Joh T
5175 - 5192	Identification of Proteins of Altered Abundance in Oil Palm Infected with Ganoderma boninense Al-Obaidi JR, Mohd-Yusuf Y, Razali N, Jayapalan JJ, Tey CC, Md-Noh N, Junit SM, Othman RY, Hashim OH