화학공학소재연구정보센터
검색결과 : 8건
No. Article
1 hERG1a/1b heteromeric currents exhibit amplified attenuation of inactivation in variant 1 short QT syndrome
McPate MJ, Zhang H, Cordeiro JM, Dempsey CE, Witchel HJ, Hancox JC
Biochemical and Biophysical Research Communications, 386(1), 111, 2009
2 Erythromycin block of the HERG K+ channel: Accessibility to F656 and Y652
Duncan RS, Ridley JM, Dempsey CE, Leishman DJ, Leaney JL, Hancox JC, Witchel HJ
Biochemical and Biophysical Research Communications, 341(2), 500, 2006
3 HERG K+ channel blockade by the antipsychotic drug thioridazine: An obligatory role for the S6 helix residue F656
Milnes JT, Witchel HJ, Leaney JL, Leishman DJ, Hancox JC
Biochemical and Biophysical Research Communications, 351(1), 273, 2006
4 The N588K-HERG K+ channel mutation in the'short QT syndrome': Mechanism of gain-in-function determined at 37 degrees C
McPate MJ, Duncan RS, Milnes JT, Witchel HJ, Hancox JC
Biochemical and Biophysical Research Communications, 334(2), 441, 2005
5 Potent inhibition of human cardiac potassium (HERG) channels by the anti-estrogen agent clomiphene - without QT interval prolongation
Yuill KH, Borg JJ, Ridley JM, Milnes JT, Witchel HJ, Paul AA, Kozlowski RZ, Hancox JC
Biochemical and Biophysical Research Communications, 318(2), 556, 2004
6 High affinity HERG K+ channel blockade by the antiarrhythmic agent dronedarone: resistance to mutations of the S6 residues Y652 and F656
Ridley JM, Milnes JT, Witchel HJ, Hancox JC
Biochemical and Biophysical Research Communications, 325(3), 883, 2004
7 Characterisation of recombinant HERG K+ channel blockade by the Class Ia antiarrhythmic drug procainamide
Ridley JM, Milnes JT, Benest AV, Masters JD, Witchel HJ, Hancox JC
Biochemical and Biophysical Research Communications, 306(2), 388, 2003
8 Inhibition of HERG potassium channel current by the Class 1a antiarrhythmic agent disopyramide
Paul AA, Witchel HJ, Hancox JC
Biochemical and Biophysical Research Communications, 280(5), 1243, 2001